Depression and Serotonin

I have a theory that my family has a problem with an imbalance of serotonin or some other neurotransmitter - and that's why we have such a high incidence of depression and being overweight. Here's an article that explains how that works - and some things you can do to improve how neurotransmitters work in your body:

Depression and Serotonin: What's the Connection?
http://www.integrativepsychiatry.net/depression_and_serotonin.html

By Valerie Balandra ARNP,BC

Depression is one of the most common and treatable of all mental illnesses. One in four women and one in 10 men can expect to develop it during their lifetime. Studies have shown that people suffering from depression have imbalances of neurotransmitters, natural substances that allow brain cells to communicate with one another. Two transmitters implicated in depression are serotonin and norepinephrine. Neurotransmitters are powerful chemicals that regulate numerous physical and emotional processes such as mental performance, emotional states and pain response. Virtually all functions in life are controlled by neurotransmitters.

Serotonin is a key neurotransmitter with many important functions in the brain and body Serotonin deficiency is a common contributor to mood problems. Some feel it is an epidemic in the United States. Serotonin is key to our feelings of happiness and very important for our emotions because it helps defend against both anxiety and depression. Many of the current biochemical theories of depression focus on the biogenic amines, which are a group of chemical compounds important in neurotransmission—most importantly norepinephrine, serotonin and, to a lesser extent, dopamine, acetylcholine and epinephrine.

What causes or contributes to Serotonin Deficiency?

• Prolonged periods of stress can deplete serotonin levels. Our fast paced, fast food society greatly contributes to these imbalances.
• Genetic factors, faulty metabolism, and digestive issues can impair absorption and breakdown of our food which reduces are ability to build serotonin.
• Poor Diet. Neurotransmitters are made in the body from proteins. Also required are certain vitamins and minerals called "cofactors". If your nutrition is poor and you do not take in enough protein, vitamins, or minerals to build the neurotransmitters, a neurotransmitter imbalance develops. We really do think and feel what we eat.
• Toxic substances like heavy metals, pesticides, drug use, and some prescription drugs can cause permanent damage to the nerve cells that make serotonin and other neurotransmitters.
• Certain drugs and substances such as caffeine, alcohol, nicotine, NutraSweet, antidepressants, and some cholesterol lowering medications deplete serotonin and other neurotransmitter levels.
• Hormone changes cause low levels of serotonin and neurotransmitter imbalances.
• Lack of sunlight contributes to low serotonin levels

Symptoms
You may have a shortage of serotonin if you have a sad depressed mood, low energy, negative thoughts, feel tense and irritable, crave sweets, and have a reduced interest in sex. Other serotonin related disorders include:

• Depression
• Anxiety
• Panic Attacks
• Insomnia
• Irritable bowel
• PMS/ Hormone dysfunction
• Fibromyalgia
• Obesity
• Eating disorders
• Obsessions and Compulsions
• Muscle pain
• Chronic Pain
• Alcohol abuse
• Migraine Headaches

How do I know if Serotonin is deficient?

Neurotransmitter testing, Questionnaires, and blood testing can help determine if you might have a serotonin deficiency. Certain test can determine if you have normal levels of the precursors and co-factor vitamins and minerals needed for the brain to produce serotonin. Additionally, hormones such as Adrenal, Thyroid, and Estrogen levels can affect serotonin levels and may explain why some women have pre-menstrual and menopausal mood problems.

How to raise serotonin levels naturally

Prescription drugs such as Prozac, Zoloft, Paxil, and Lexapro are classified as serotonin reuptake inhibitors, or (SSRI's). They help to keep more of the serotonin your brain is making in circulation. They are used for a wide variety of symptoms such as depression, panic attacks, anxiety, PTSD, obsessions, and compulsions. There are serotonin/norepinephrine re-uptake inhibitors (SNRI's) such as Effexor and Cymbalta that keep more serotonin and norepinephrine in circulation.

Nutrient therapies such as Targeted Amino Acid Therapy naturally increase the levels of neurotransmitters that a person has been found to be deficient in.5 hydroxytryptophan and Tryptophan are widely known for their ability to help depressive symptoms by raising serotonin levels in the brain.. Numerous clinical trials have studied the efficacy of 5-HTP for treating depression. One compared 5-HTP to the antidepressant drug fluvoxamine and found 5-HTP to be equally effective.

It can be used alone or in combination with medication to keep dosages low and to prevent the "poop out" many people experience with medication.

• tryptophan —> 5-HTP —> serotonin

Herbal Remedies such as St. Johns Wort are available to alleviate symptoms of depression and anxiety. Some work in a similar way to the SSRI antidepressants.

Things you can do to increase your serotonin levels and improve overall health.

• Exercise at least 30 minutes three times a week.
• Walking, yoga, stretching.
• Get plenty of sunlight.
• Drink 6-8 glasses of water daily
• Prayer and meditation

Eat at least three meals per day. Skipping meals promotes high stress and low energy. Eat protein with every meal. Eat Complex carbohydrates such as brown rice. Avoid sugar, junk food, white pasta, white rice, white bread, cookies and cake. No Caffeine, alcohol, or NutraSweet (aspartame). NutraSweet can be toxic to your brain. Alcohol can worsen depression, anxiety, and sleep problems.

Bananas

After Reading THIS, you'll NEVER look at a banana in the same way again!

Bananas Containing three natural sugars - sucrose, fructose and glucose combined with fiber, a banana gives an instant, sustained and substantial boost of energy. Research has proven that just two bananas provide enough energy for a strenuous 90-minute workout. No wonder the banana is the number one fruit with the world's leading athletes. But energy isn't the only way a banana can help us keep fit. It can also help overcome or prevent a substantial number of illnesses and conditions, making it a must to add to our daily diet.

Depression:
According to a recent survey undertaken by MIND amongst people suffering from depression, many felt much better after eating a banana. This is because bananas contain tryptophan, a type of protein that the body converts into serotonin, known to make you relax, improve your mood and generally make you feel happier.

PMS:
Forget the pills -- eat a banana. The vitamin B6 it contains regulates blood glucose levels, which can affect your mood.

Anemia:
High in iron, bananas can stimulate the production of hemoglobin in the blood and so helps in cases of anemia.

Blood Pressure:
This unique tropical fruit is extremely high in potassium yet low in salt, making it the perfect way to beat blood pressure. So much so, the US Food and Drug Administration has just allowed the bana na industry to make official claims for the fruit's ability to reduce the risk of blood pressure and stroke.

Brain Power:
200 students at a Twickenham (Middlesex) school were helped through their exams this year by eating bananas at breakfast, break, and lunch in a bid to boost their brain power. Research has shown that the potassium-packed fruit can assist learning by making pupils more alert.

Constipation:
High in fiber, including bananas in the diet can help restore normal bowel action, helping to overcome the problem without resorting to laxatives.

Hangovers:
! One of t he quickest ways of curing a hangover is to make a banana milkshake, sweetened with honey. The banana calms the stomach and, with the help of the honey, builds up depleted blood sugar levels, while the milk soothes and re-hydrates your system.

Heartburn:
Bananas have a natural antacid effect in the body, so if you suffer from heartburn, try eating a banana for soothing relief.

Morning Sickness:
Snacking on bananas between meals helps to keep blood sugar levels up and avoid morning sickness.

Mosquito bites:
Before reaching for the insect bite cream, try rubbing the affected area with the inside of a banana skin. Many people find it amazingly successful at reducing swelling and irritation.

Nerves:
Bananas are high in B vitamins that help calm the nervous system.

Overweight and at work?
Studies at the Institute of Psychology in Austria found pressure at work leads to gorging on comfort food like chocolate and chips. Looking at 5,000 hospital patients, researchers found the most obese were more likely to be in high-pressure jobs. The report concluded that, to avoid panic-induced food cravings, we need to control our blood sugar levels by snacking on high carbohydrate foods every two hours to keep levels steady.

Ulcers:
The banana is used as the dietary food against intestinal disorders because of its soft texture and smoothness. It is the only raw fruit that can be eaten without distress in over-chronicler cases. It also neutralizes over-acidity an d reduces irritation by coating the lining of the stomach.

Temperature control:
Many other cultures see bananas as a "cooling" fruit that can lower both the physical and emotional temperature of expectant mothers. In Thailand, for example, pregnant women eat bananas to ensure their baby is born with a cool temperature.

Seasonal Affective Disorder (SAD):
Bananas can help SAD sufferers because they contain the natural mood enhancer tryptophan.

Smoking:
Bananas can also help people trying to give up smoking. The B6, B12 they contain, as well as the potassium and magnesium found in them, help the body recover from the effects of nicotine withdrawal.

Stress:
Potassium is a vital mineral, which helps normalize the heartbeat, sends oxygen to the brain and regulates your body's water balance. When we are stressed, our metabolic rate rises, thereby reducing our potassium levels. These can be rebalanced with the help of a high-potassium banana snack.

Strokes:
According to research in "The New England Journal of Medicine," eating bananas as part of a regular diet can cut the risk of death by strokes by as much as 40%!

So, a banana really is a natural remedy for many ills. When you compare it to an apple, it has four times the protein, twice the carbohydrates, three times the phosphorus, five times the vitamin A and iron, and twice the other vitamins and minerals. It is also rich in potassium and is one of the best value foods around. So maybe its time to change that well-known phrase so tha t we say, "A banana a day keeps the doctor away!"